A Review on Antibiotic Resistance: Alarm Bells are Ringing
By Sojib Bin Zaman, M. Hussain, Rachel Nye, Varshil Mehta, Kazi Taib Mamun, Naznin Hossain. Cureus, 2017
755 citations recorded by the source corpus.
Antibiotics are the ‘wonder drugs’ to combat microbes. For decades, multiple varieties of antibiotics have not only been used for therapeutic purposes but practiced prophylactically across other industries such as agriculture and animal husbandry. Uncertainty has arisen, as microbes have become resistant to common antibiotics while the host remains unaware that antibiotic resistance has emerged. The aim of this review is to explore the origin, development, and the current state of antibiotic resistance, regulation, and challenges by examining available literature. We found that antibiotic resistance is increasing at an alarming rate. A growing list of infections i.e., pneumonia, tuberculosis, and gonorrhea are becoming harder and at times impossible to treat while antibiotics are becoming less effective. Antibiotic-resistant infections correlate with the level of antibiotic consumption. Non-judicial use of antibiotics is mostly responsible for making the microbes resistant. The antibiotic treatment repertoire for existing or emerging hard-to-treat multidrug-resistant bacterial infections is limited, resulting in high morbidity and mortality report. This review article reiterates the optimal use of antimicrobial medicines in human and animal health to reduce antibiotic resistance. Evidence from the literature suggests that the knowledge regarding antibiotic resistance in the population is still scarce. Therefore, the need of educating patients and the public is essential to fight against the antimicrobial resistance battle.
Subfields: Applied Microbiology and Biotechnology, Molecular Medicine, Pollution
View Paper: https://www.semanticscholar.org/paper/5483e1794d83a4e1faddd897d8afab7eba2d561a
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In Molecular Medicine
In Pollution
Citations in the corpus
- Antimicrobial Resistance: A Growing Serious Threat for Global Public Health (2023, background): “Levofloxacin, a member of the third-generation fluoroquinolone, was added to the antibiotics list in 1996, and levofloxacin-resistant Pneumococcus was reported in the same year [20].”
- Antibiotic resistance and persistence—Implications for human health and treatment perspectives (2020, neutral): “There are many excellent reviews already published focusing on antibiotic resistance (Turnidge & Christiansen, 2005; Spellberg et al , 2013; Blair et al , 2015; Foster, 2017; Rather et al , 2017; Zaman et al , 2017; Aslam et al , 2018; Jorge et al , 2019; Lopez-Jacome et al , 2019).”