Fast-spiking, parvalbumin+ GABAergic interneurons: From cellular design to microcircuit function

By Hua Hu, J. Gan, Peter Jonas. 2014

1,120 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

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Citations in the corpus

Re-evaluating circuit mechanisms underlying pattern separation (2019, positive): “In addition, recent work has found that parvalbumin-expressing interneurons (which includes some basket cells as well as axo-axonic cells; Hu et al., 2014) establish powerful lateral inhibition between granule cells (Espinoza et al., 2018).”
Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics (2017, positive): “Consistent with this, we found that expression of fast-spiking associated genes such as Kcnc1 was on average lower in clusters corresponding to Cck interneurons, but that some cells still expressed these genes.”
A Single-Cell Atlas of Cell Types, States, and Other Transcriptional Patterns from Nine Regions of the Adult Mouse Brain (2018, background): “…6). pericytes, which associate with small-diameter capillaries and are enriched for Rgs5 expression, and smooth muscle alpha actin (SMA) cells, which associate with larger-bore arterioles and express Acta2 (Bondjers, 2006; He et al., 2016; Hughes and Chan-Ling, 2004; Nehls and Drenckhahn, 1991).”
Why Neurons Have Thousands of Synapses, a Theory of Sequence Memory in Neocortex (2015, background): “Fast-spiking basket inhibitory cells are the most likely source for this rapid inhibition (Hu et al., 2014).”
Inhibitory circuits of the mammalian main olfactory bulb. (2017, background): “…2013; Lepousez et al. 2010; Toida et al. 1994, 1996), including basketlike innervation of some M/TC somata (Crespo et al. 2002, 2013; Kosaka and Kosaka 2008b), which likely functions similarly to the powerful perisomatic inhibition of pyramidal cells by basket cell interneurons (Hu et al. 2014).”
Constitutive and Synaptic Activation of GIRK Channels Differentiates Mature and Newborn Dentate Granule Cells (2018, background): “…GABABR and GIRK channels coincides with a marked polarity in the axonal distribution of the different interneuron populations in the DG. Parvalbumin-expressing interneurons are primarily fast-spiking basket cells that target axons to the granular layer (Freund and Buzsáki, 1996; Hu et al., 2014).”