NRAS Mutation Status is an Independent Prognostic Factor in Metastatic Melanoma

By J. Jakob, Roland L. Bassett, Chaan S Ng, Jonathan L. Curry, Richard W. Joseph, G. Alvarado, M. Rohlfs, J. Richard, J. Gershenwald, P. Hwu and 3 more. Cancer, 2011

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There is a need for improved prognostic markers in melanoma. In this study, the authors tested the prognostic significance and clinicopathologic correlations of v‐raf murine sarcoma viral oncogene homolog B1 (BRAF) and neuroblastoma RAS viral (v‐ras) oncogene homolog (NRAS) mutations in patients with metastatic melanoma.

Subfields: Molecular Biology, Oncology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/538da8f0876196b8ec6e234351194300fe63bb34