End of the beginning

By S. Segawa. 1990

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

A robotic platform for flow synthesis of organic compounds informed by AI planning (2019, methodology): “A stereoretentive route to the chiral drug substance safinamide (18) was identified by the synthesis-planning program using L-alaninamide (20).”
Prediction of higher-selectivity catalysts by computer-driven workflow and machine learning (2019, unknown): “Computer-assisted synthetic planning (5, 6), the prediction of organic reaction outcomes (7, 8), assisted medicinal chemistry discovery (9, 10), catalyst design (11, 12), the use of continuous molecular representations for automatic generation of new chemical structures (13), materials discovery (14”
Machine learning for molecular and materials science (2018, background): “In a synthetic chemistry route, the number of possible transformations per step can range from around 80 to several thousand,(34) which compares to the order of tens of potential moves at each game position in chess.(35) In chemical synthesis, human experts are required to specify conditional and co”
High resolution structure of the large ribosomal subunit from a mesophilic eubacterium. (2001, unknown): “Contrary to L27, the tail of translational factors, and in factor-dependent GTPase L21e folds backward, toward the interior of the subunit, activity (Chandra Sanyal and Liljas, 2000).”