Is a low transfusion threshold safe in critically ill patients with cardiovascular diseases?

By P. Hebert, E. Yetisir, C. Martin, M. Blajchman, G. Wells, J. Marshall, M. Tweeddale, G. Pagliarello, I. Schweitzer. Critical Care Medicine, 2001

635 citations recorded by the source corpus.

Subfields: Biochemistry, Critical Care and Intensive Care Medicine, Epidemiology

View Paper: https://www.semanticscholar.org/paper/531fd8682d1919343fdf7579680058afada2b35f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. P. Marik

In Critical Care and Intensive Care Medicine

1. P. Marik
2. Mitchell M. Levy

In Epidemiology

1. P. Marik
2. Eric J. Topol
3. Mitchell M. Levy

Citations in the corpus

• Efficacy of red blood cell transfusion in the critically ill: A systematic review of the literature* (2008, background): “There remains controversy as to the appropriate transfusion thresholds for patients with ischemic cardiac disease and in the early resuscitation of patients with septic shock (71, 83, 84).”
• Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes. (2004, result): “ease, supported the overall results.(9) In contrast, an observational study of elderly patients with acute myocardial infarction (MI) found an association between transfusion and improved shortterm survival when hematocrit at admission was 30% to 33% or less.”
• The CRIT Study: Anemia and blood transfusion in the critically ill—Current clinical practice in the United States* (2004, result): “This finding also seemed to apply to patients with underlying cardiac disease, although other data suggest that patients with active ischemic cardiac disease may require a higher hemoglobin level (11).”