PI3K/Akt signalling pathway and cancer.

By J. Á. Fresno Vara, E. Casado, J. de Castro, P. Cejas, C. Belda-Iniesta, M. González-Barón. Cancer Treatment Reviews, 2004

2,405 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/5282885080cbcdc8e4f21e3e2b19e2d4b027bf64

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. C. Paglino
2. H. Rupasinghe
3. C. Porta
4. E. McGowan
5. Naiara Orrego Lagarón
6. A. Mosca
7. Indu Parmar
8. A. Jha

Citations in the corpus

• Targeting PI3K/Akt/mTOR Signaling in Cancer (2014, background): “PI3,4,5-P3 then recruits a subset of signaling proteins with pleckstrin homology (PH) domains to the membrane, including protein serine/threonine kinase-3′-phosphoinositide-dependent kinase 1 (PDK1) and Akt/protein kinase B (PKB) (5, 6).”
• Kinase-targeted cancer therapies: progress, challenges and future directions (2018, background): “Akt, a crucial kinase modulates diverse cellular processes involved in the regulation of cell survival, cell cycle progression and cellular growth [223].”