Microrheology with optical tweezers: data analysis

By M. Tassieri, R. Evans, Rebecca L. Warren, Nicholas J. Bailey, Jonathan M. Cooper. 2012

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We present a data analysis procedure that provides the solution to a long-standing issue in microrheology studies, i.e. the evaluation of the fluids' linear viscoelastic properties from the analysis of a finite set of experimental data, describing (for instance) the time-dependent mean-square displacement of suspended probe particles experiencing Brownian fluctuations. We report, for the first time in the literature, the linear viscoelastic response of an optically trapped bead suspended in a Newtonian fluid, over the entire range of experimentally accessible frequencies. The general validity of the proposed method makes it transferable to the majority of microrheology and rheology techniques.

Subfields: Atomic and Molecular Physics, and Optics, Biomedical Engineering, Plant Science

View Paper: https://www.semanticscholar.org/paper/51a1eedd581f24019f844ccd6b60e44eacc6c0a4