THE GENETIC ARCHITECTURE OF ADAPTATION UNDER MIGRATION–SELECTION BALANCE

By Sam Yeaman, M. Whitlock. Evolution; international journal of organic evolution, 2011

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View Paper: https://www.semanticscholar.org/paper/5161ebcb26e89a9b424114de0330c680375af072

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In Genetics

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Where am I and why? Synthesizing range biology and the eco-evolutionary dynamics of dispersal (2014, background): “Holt and Barfield (2011; see also Yeaman and Whitlock 2011) demonstrate that genetic architecture (e.g. the number of loci contributing substantially to genetic variance in a trait) can itself evolve substantially under the combined influence of gene flow, mutation, and local adaptation in…”
Potential for evolutionary responses to climate change – evidence from tree populations (2013, background): “While the traditional polygenic model of Fisher (Fisher, 1918, 1930) is based on small effects at a very large number of loci, some models of selection predict larger effect sizes (Orr, 1998; Yeaman & Whitlock, 2011).”
Assisted Gene Flow to Facilitate Local Adaptation to Climate Change (2013, background): “…amount of genetic variation available to local populations can be too low to allow effective adaptation if the effective population size is small (Yeaman & Whitlock 2011, Blanquart et al. 2012), so local adaptation is more often expected when the local population size is large [as was observed…”
The genomics of local adaptation in trees: are we out of the woods yet? (2017, background): “…below a critical threshold, and over many thousands of generations, there is an increase in the probability of establishment and persistence times of large-effect alleles, thus reducing the proportion of the polymorphism due to small-effect loci (Yeaman and Otto 2011; Yeaman and Whitlock 2011).”