Long‐term results of a randomized trial comparing preoperative short‐course radiotherapy with preoperative conventionally fractionated chemoradiation for rectal cancer

By K. Bujko, M. Nowacki, A. Nasierowska-Guttmejer, W. Michalski, M. Bębenek, M. Kryj. British Journal of Surgery, 2006

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Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. (2017, neutral): “No differences in oncological outcomes between CRT and SCPRT were reported in two prospective studies offering preoperative therapy in unselected clinically determined T3/T4 or nodepositive rectal cancer patients [54, 55].”
Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer (2012, background): “In two trials (the exception being the short-course radiotherapy trial), the local recurrence rate was significantly lower in the preoperative chemoradiotherapy group, and there was no significant difference between the two groups in terms of sphincter preservation or survival rate [65–67].”