Surface Plasmon Resonance: A Versatile Technique for Biosensor Applications

By Hoang Hiep Nguyen, Jeho Park, Sebyung Kang, Moonil Kim. Italian National Conference on Sensors, 2015

1,174 citations recorded by the source corpus.

Surface plasmon resonance (SPR) is a label-free detection method which has emerged during the last two decades as a suitable and reliable platform in clinical analysis for biomolecular interactions. The technique makes it possible to measure interactions in real-time with high sensitivity and without the need of labels. This review article discusses a wide range of applications in optical-based sensors using either surface plasmon resonance (SPR) or surface plasmon resonance imaging (SPRI). Here we summarize the principles, provide examples, and illustrate the utility of SPR and SPRI through example applications from the biomedical, proteomics, genomics and bioengineering fields. In addition, SPR signal amplification strategies and surface functionalization are covered in the review.

Subfields: Molecular Biology, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/514ccd4d62209815d1c15251e5fc8141aead4442

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Sun Hyeok Lee
2. C. Fermin
3. Ui Jin Lee
4. Hoang Hiep Nguyen
5. Moonil Kim

In Radiology, Nuclear Medicine and Imaging

1. Hoang Hiep Nguyen
2. Moonil Kim

Citations in the corpus

• Label-free optical biosensors for food and biological sensor applications (2018, neutral): “The technique measures the change in refractive index within he ambit of thin metal layers like gold, aluminium or silver films ith respect to the biomolecular interactions [10].”
• Immobilized Enzymes in Biosensor Applications (2019, background): “A thorough review on SPR-based biosensor applications is found here [113].”
• Applications and Advances in Bioelectronic Noses for Odour Sensing (2018, background): “Lee et al. employed SPR system to characterize molecular interactions between olfactory receptors and their cognate odour molecules [29].”