RNA-based antiviral immunity

By Shou-Wei Ding. Nature reviews. Immunology, 2010

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Current knowledge of interactions between Drosophila suzukii and microbes, and their potential utility for pest management (2016, background): “RNA interference (RNAi) co-opts a cellular mechanism that likely evolved to protect eukaryotes from RNA viruses, introducing exogenous double-stranded RNA (dsRNA) to activate the cellular machinery to degrade or suppress the translation of gene transcripts complementary to the dsRNA (Ding 2010; Bura”
Recent advances in RNA interference research in insects: Implications for future insect pest management strategies (2013, background): “mechanism is hypothesized to represent an active organismal response against viral infection and mobilized transposable elements, as well as playing a role in developmentally regulated translational suppression (Ding, 2010).”
The Logic of Chance: The Nature and Origin of Biological Evolution (2011, background): “” Moreover, the system has a degree of memory because, in many organisms, siRNAs are amplified, and the resistance to the cognate virus can persist for several generations (Ding, 2010).”