The evolution of transcriptional regulation in eukaryotes.

By Gregory A. Wray, Matthew W. Hahn, E. Abouheif, James P. Balhoff, M. Pizer, M. Rockman, L. Romano. Molecular biology and evolution, 2003

1,183 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/511e19d0ecd87fcc758b7bc94da4f514feccc4b5

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Citations in the corpus

Non-coding nuclear DNA markers in phylogenetic reconstruction (2009, background): “Those transcription factor-binding sites are usually arranged in clusters of 6–15, thus exhibiting modular organisation (Fickett and Wasserman 2000; Wray et al. 2003).”
Transposable elements and the evolution of regulatory networks (2008, background): “Most cis -regulatory elements, such as TFBSs, tend to be short and degenerate in sequenc”
Heavy Metal Tolerance in Plants: Role of Transcriptomics, Proteomics, Metabolomics, and Ionomics (2016, background): “Studies reveal that a single TF can control the expression of many target genes via specific binding of the TF to the cis-acting element in the promoters of its target genes (Wray et al., 2003; Nakashima et al., 2009).”
The Loci of Evolution: How Predictable is Genetic Evolution? (2008, background): “For example, a few genes are known to contain transcription factor binding sites in exons (keratin18 in humans and nonA in Drosophila melanogaster [Wray et al. 2003]).”
L. A. S. JOHNSON REVIEW No. 2 Use of nuclear genes for phylogeny reconstruction in plants (2004, background): “Important promoter elements responsible for gene regulation are generally found in the 5′ UTR which may include relatively conserved domains (Wray et al. 2003).”
Long-range control of gene expression: emerging mechanisms and disruption in disease. (2005, background): “…emerging view is that the growth in evolutionary complexity is predominantly brought about by increasing regulatory intricacy (Carroll et al. 2001; Levine and Tjian 2003) and that a significant component of this is through alterations in cis regulation (Wray et al. 2003; Howard and Davidson 2004).”
Evolution of Gene Duplication in Plants1[OPEN] (2016, background): “…functions can arise from the co-option of existing genes (True and Carroll, 2002), new genes can arise de novo from intergenic space (Tautz and Domazet-Lošo, 2011; Schlötterer, 2015), and new transcriptional regulatory sites can come into existence that alter gene expression (Wray et al., 2003).”
Similarities and Differences in Genome-Wide Expression Data of Six Organisms (2003, background): “So far, however, such an approach has been mostly applied to small numbers of genes (Carroll 2000; True and Carroll 2002; Wray et al. 2003) or has been restricted to variations in the genome-wide expression profiles during the development of closely related species (Rifkin et al.”
Evolutionary Transitions in Floral Color (2008, background): “Cis-regulatory mutations that greatly reduce the expression of an anthocyanin structural gene or transcription factor are the most probable candidates for reversal because lost promoter binding sites can be recovered by a variety of mutational processes (Wray et al. 2003).”
Applied bioinformatics for the identification of regulatory elements (2004, background): “Two recent reports have indicated conservation of only ∼50% of human/mouse regulatory site”
THE LOCUS OF EVOLUTION: EVO DEVO AND THE GENETICS OF ADAPTATION (2007, background): “GENOMIC STUDIES OF cis AND trans MUTATIONS It is appropriate to begin our discussion with recent genomic data, because much of the inspiration for “regulatory gene” theories arose from early genomic data on the similarity of protein sequences between humans and chimps.”
PlnTFDB: an integrative plant transcription factor database (2007, background): “A deep understanding of transcription factors and their regulatory networks would also improve our understanding of organism diversity [2,3].”
The convergent evolution of aluminium resistance in plants exploits a convenient currency (2010, background): “Modifications to the target sequences and cis-regulatory elements can influence evolutionary change just as mutations in the coding regions do by changing protein function (Wray et al. 2003).”
Convergent adaptation of human lactase persistence in Africa and Europe (2006, background): “In conclusion, multiple independent variants have allowed various human populations to quickly modify LCT expression and have been strongly adaptive in adult milk-consuming populations, emphasizing the importance of regulatory mutations in recent human evolutio”