Eosinophilic esophagitis.
By Anand Gupte, P. Draganov. World Journal of Gastroenterology, 2009
897 citations recorded by the source corpus.
Eosinophilic esophagitis is increasingly recognized in adults. The diagnosis is based on the presence of both typical symptoms and pathologic findings on esophageal biopsy. Patients usually present with dysphagia, food impaction and/or reflux-like symptoms, and biopsy of the esophagus shows more than 15 eosinophils per high-power field. In addition, it is essential to exclude the presence of known causes of tissue eosinophilia such as gastroesophageal reflux disease, infections, malignancy, collagen vascular diseases, hypersensitivity, and inflammatory bowel disease. There are no standardized protocols for the therapy of eosinophilic esophagitis. A variety of therapeutic approaches including acid suppression, dietary modifications, topical corticosteroids and endoscopic dilation can be used alone or in combination.
Subfields: Rheumatology, Surgery
View Paper: https://www.semanticscholar.org/paper/50d2734ba5f1da7a15f96972b8c7d394e48c8950
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In Rheumatology
Citations in the corpus
- Eosinophils: Biological Properties and Role in Health and Disease (2008, background): “…1988), allergic colitis (Sherman & Cox 1982; Hill & Milla 1990; Odze et al. 1995), eosinophilic esophagitis (Furuta 1998; Rothenberg et al. 2001b; Fox et al. 2002), inflammatory bowel disease (IBD) (Sarin et al. 1978; Dvorak 1980; Walsh & Gaginella 1991), and gastroesophageal reflux disease…”