Reduction-sensitive polymers and bioconjugates for biomedical applications.
By F. Meng, W. E. Hennink, Zhiyuan Zhong. Biomaterials, 2009
1,050 citations recorded by the source corpus.
Subfields: Molecular Biology, Organic Chemistry
View Paper: https://www.semanticscholar.org/paper/4ff33c83b0bdbd82d4df4c11080978ab35ad63e4
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In Molecular Biology
In Organic Chemistry
Citations in the corpus
- Glutathione-responsive nano-vehicles as a promising platform for targeted intracellular drug and gene delivery. (2011, background): “In the past several years, significant effort has been directed to development of reduction-responsive gene delivery systems [13,85].”
- pH Sensitive Hydrogels in Drug Delivery: Brief History, Properties, Swelling, and Release Mechanism, Material Selection and Applications (2017, background): “This cleavage of disulfide linkages is responsible for the release of drug or bioactive agents in the intracellular matrix [46].”
- Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery. (2013, background): “pH and redox are the two most appealing stimuli, as they both exist naturally in certain pathological sites as well as in all cancer cells [11,15].”
- Smart nanocarrier-based drug delivery systems for cancer therapy and toxicity studies: A review (2018, background): “The intra-cellular concentration of GSH is 1000 times higher than in the blood stream [70,184].”