Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets
By Joon-Il Jun, L. Lau. Nature reviews. Drug discovery, 2011
611 citations recorded by the source corpus.
Subfields: Immunology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/4fe7acf0628c741919a7e8804e30182076448ebc
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In Immunology
In Molecular Biology
Citations in the corpus
- Hallmarks of Cellular Senescence. (2018, neutral): “For example, senescent cells associated with tissue repair express several MMPs and growth factors, such as PDGF-A and VEGF [6,78], while age-associated or therapy-induced senescent cells are mainly associated with inflammatory factors [79,80].”
- The myofibroblast matrix: implications for tissue repair and fibrosis (2013, positive): “Despite the designation as a growth factor, CCN2 is not a cytokine but an integral ECM protein that exerts its function through binding of cell integrins alone or recruitment of co-receptors [145].”