Characterization of VIM-2, a Carbapenem-Hydrolyzing Metallo-β-Lactamase and Its Plasmid- and Integron-Borne Gene from a Pseudomonas aeruginosa Clinical Isolate in France
By L. Poirel, T. Naas, Delphine Nicolas, L. Collet, Samuel Bellais, J. Cavallo, P. Nordmann. Antimicrobial Agents and Chemotherapy, 2000
618 citations recorded by the source corpus.
Subfields: Endocrinology, Molecular Biology, Molecular Medicine
View Paper: https://www.semanticscholar.org/paper/4f8770064f4c062cbb1757c0e5987f1b1dd395d3
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Citations in the corpus
- Characterization of a New Metallo-β-Lactamase Gene, blaNDM-1, and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India (2009, background): “The role of these substitutions is not apparent, as NDM-1 possesses kinetics similar to those of VIM-2 (23, 29).”
- Carbapenemases: the Versatile β-Lactamases (2007, methodology): “aeruginosa strains with VIM, IMP, GIM, SIM, and SPM metallo- -lactamases, imipenem MICs have been reported in the range of 8 to 128 g/ml (26, 101, 104, 126, 171, 204, 228).”
- Plasmid encoded antibiotic resistance: acquisition and transfer of antibiotic resistance genes in bacteria (2008, background): “More recently identified antibiotic resistance gene cassettes include those that encode the metallo-b-lactamases IMP and VIM (Laraki et al., 1999; Lauretti et al., 1999; Poirel et al., 2000; Riccio et al., 2000; Nordmann and Poirel, 2002) (Figure 8), which confer resistance to the potent carbapenem ”
- The difficult-to-control spread of carbapenemase producers among Enterobacteriaceae worldwide. (2014, neutral): “aeruginosa isolate dating from 1996 [43].”
- The Epidemiology of Carbapenem-Resistant Enterobacteriaceae: The Impact and Evolution of a Global Menace (2017, background): “The VIM-type MBLs were described in 1996 and 1997 in P. aeruginosa from Verona, Italy (VIM-1), and Marseilles, France (VIM-2) [43, 44].”
- Epidemiology of β-Lactamase-Producing Pathogens (2020, background): “The enzymes were not closely related to other MBLs based on amino acid sequences, with only 28 to 31% sequence identity between the VIM-1/VIM-2 carbapenemases and IMP-1 (64, 294).”
- Emerging carbapenemases in Gram-negative aerobes. (2002, background): “Bla VIM-2 was identified first in southern France (Marseilles), not far from Italy, from a P. aeruginosa isolate in a blood culture of a neutropenic patient in 1996 [45].”