Auxin transport inhibitors block PIN1 cycling and vesicle trafficking

By N. Geldner, Jir□í Friml, York Stierhof, G. Jürgens, Klaus Palme. Nature, 2001

1,268 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/4f72c4779a8e89ff843867af8d7bbe4a66f1b93a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

In Plant Science

Citations in the corpus

The role of cytoplasmic streaming in symplastic transport (2003, neutral): “Its polar transport is believed to require asymmetric vesicle-trafficking of the efflux carrier candidate PIN1, which localizes in basal cell walls where it promotes auxin efflux into the cell wall space (Palme & Gälweiler 1999; Geldner et al. 2001).”
Regulation of phyllotaxis by polar auxin transport (2003, background): “Indeed, cellular redistribution of the PIN1 protein can be extremely rapi”
The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis roots (2005, background): “Mutations in the ARF-GEF GNOM, required for vesicle transport of PIN1, also lead to developmental defects that resemble those caused by interfering with auxin transpor”
Auxin: the looping star in plant development. (2008, background): “In their model the localized auxin sources also provide an explanation for the formation of discontinuous veins, something that is observed in vesicle trafficking mutants such as gnom and van3 (44, 45, 62).”
Expression dynamics of WOX genes mark cell fate decisions during early embryonic patterning in Arabidopsis thaliana (2004, background): “Polar localization of PIN1 at one side of the cell is established by intracellular vesicle transport mediated by GNOM/EMB30 (GN) activity and predicts the directionality of auxin flow (Busch et al., 1996; Geldner et al., 2001; Shevell et al., 1994; Steinmann et al., 1999).”
Auxin: a trigger for change in plant development. (2009, neutral): “, 2007) and ARF GEF-dependent exocytosis (Geldner et al., 2001).”
Auxin promotes Arabidopsis root growth by modulating gibberellin response (2003, background): “, and is thought to be the site of NPA-mediated inhibition of polar auxin transpor”
SCD1 is required for cell cytokinesis and polarized cell expansion in Arabidopsis thaliana (2003, neutral): “At the concentrations of BFA used in these experiments plant Golgi remain intact but secretion is inhibited (Geldner et al., 2001; Staehelin and Driouich, 1997).”
Vacuolar H+-ATPase Activity Is Required for Endocytic and Secretory Trafficking in Arabidopsis[W] (2006, background): “BFA has been instrumental in demonstrating the constitutive cycling of plant proteins between the plasma membrane and endosomal compartments (Geldner et al., 2001), but it V-ATPase and Vesicle Trafficking 725”
Intracellular trafficking and proteolysis of the Arabidopsis auxin-efflux facilitator PIN2 are involved in root gravitropism (2006, methodology): “In this context, it is significant that the control of PIN protein function has been associated with its constitutive cycling between the plasma membrane and endosomes, as demonstrated by treatment with BF”
PIN-Dependent Auxin Transport: Action, Regulation, and Evolution (2015, background): “A candidate for the protein that may mediate this BFA-sensitive polar delivery of PIN1 is the ARFGEF GNOM. gnom mutants demonstrate severe defects in development, characterized, in extreme cases, by a complete loss of apical-basal body plan (Mayer et al., 1991; Shevell et al., 1994).”
Regulation of Root Growth by Plant Hormones—Roles for Auxin and Gibberellin (2005, background): “Although the mechanism is not clear at this time, it has been suggested the localization of PIN proteins occurs by the asymmetric vesicular targeting mechanism (Muday, 2000; Geldner et al., 2001; Muday and Murphy, 2002; Grebe et al., 2002; Geldner et al., 2003).”