Mitochondrial genome organization and vertebrate phylogenetics
By S. L. Pereira. 2000
131 citations recorded by the source corpus.
With the advent of DNA sequencing techniques the organization of the vertebrate mitochondrial genome shows variation between higher taxonomic levels. The most conserved gene order is found in placental mammals, turtles, fishes, some lizards and Xenopus. Birds, other species of lizards, crocodilians, marsupial mammals, snakes, tuatara, lamprey, and some other amphibians and one species of fish have gene orders that are less conserved. The most probable mechanism for new gene rearrangements seems to be tandem duplication and multiple deletion events, always associated with tRNA sequences. Some new rearrangements seem to be typical of monophyletic groups and the use of data from these groups may be useful for answering phylogenetic questions involving vertebrate higher taxonomic levels. Other features such as the secondary structure of tRNA, and the start and stop codons of protein-coding genes may also be useful in comparisons of vertebrate mitochondrial genomes.
Subfields: Molecular Biology, Plant Science
View Paper: https://www.semanticscholar.org/paper/4f3260493c1596c4fdbcdfc6ed9f9e72ee2c24a4
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In Molecular Biology
Citations in the corpus
- Evolution of the mitochondrial genome of Metazoa as exemplified by comparison of congeneric species (2008, background): “In fact, the dogma of a frozen gene order in vertebrates has been broken by the identification of several deviations from the ‘typical’ gene order in marsupials, birds, crocodiles, reptiles, amphibians, bony fishes and lampreys (Boore, 1999; Pereira, 2000; Inoue et al., 2003).”