Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update

By M. Schachter. Fundamental & Clinical Pharmacology, 2005

1,211 citations recorded by the source corpus.

Subfields: Computational Theory and Mathematics, Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/4eed469ed9094d1202ecd240f57fe0128b0944d1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Computational Theory and Mathematics

1. E. Candelario-Jalil
2. Ryan G. Coleman
3. Surojit Paul

In Molecular Biology

1. E. Candelario-Jalil
2. Ryan G. Coleman
3. Enoch S. Huang
4. Qing Cao
5. Kathleen T Smyth
6. Daniel R. Caffrey
7. Alan C. Cheng
8. Anna C. Salzberg

In Surgery

1. E. Candelario-Jalil
2. Surojit Paul

Citations in the corpus

• Structure-based maximal affinity model predicts small-molecule druggability (2007, background): “Some first generation statins are delivered as prodrugs, and the mechanism of statin drug action requires high first-pass effect but does not require high bioavailability because the liver is the target orga”
• Emerging Neuroprotective Strategies for the Treatment of Ischemic Stroke: An Overview of Clinical and Preclinical Studies (2020, background): “Statins are either fungal-derived (lovastatin, pravastatin and simvastatin) or fully synthetic compounds (atorvastatin, cerivastatin, pitavastatin, rosuvastatin and fluvastatin) (Schachter, 2005).”