ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties

By Binlei Liu, M. Robinson, Ziqun Han, R. Branston, C. English, P. Reay, Y. McGrath, S. Thomas, M. Thornton, P. Bullock and 2 more. Gene Therapy, 2003

801 citations recorded by the source corpus.

Subfields: Epidemiology, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4ed00647a33765668fe6bc18183049ca792eee92

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Citations in the corpus

• Oncolytic viruses: a new class of immunotherapy drugs (2015, background): “Studies of HSV-1 in mice demonstrated rejection of contralateral, un-injected flank tumours only when GM-CSF, a cytokine that promotes dendritic cell accumulation and maturation, was engineered into the viral genome 74, 79 .”