Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later

By Allison M. Bond, Guo-li Ming, Hongjun Song. Cell Stem Cell, 2015

746 citations recorded by the source corpus.

Summary Adult somatic stem cells in various organs maintain homeostatic tissue regeneration and enhance plasticity. Since its initial discovery five decades ago, investigations of adult neurogenesis and neural stem cells have led to an established and expanding field that has significantly influenced many facets of neuroscience, developmental biology and regenerative medicine. Here we review recent progress and focus on questions related to adult mammalian neural stem cells that also apply to other somatic stem cells. We further discuss emerging topics that are guiding the field toward better understanding adult neural stem cells and ultimately applying these principles to improve human health.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4e7750a9d7fda0fbc94d557acc4b1ce52bd599b7

Citations in the corpus

• Zika Virus Infects Human Cortical Neural Precursors and Attenuates Their Growth (2016, neutral): “Our study also raises the question of whether ZIKV infects neural stem cells in adult humans (Bond et al., 2015).”