Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

By Geoffrey Hom, R. Graham, Barmak Modrek, K. Taylor, W. Ortmann, S. Garnier, Annette T. Lee, Sharon A Chung, Ricardo C. Ferreira, P. Pant and 17 more. New England Journal of Medicine, 2008

966 citations recorded by the source corpus.

Subfields: Immunology, Rheumatology

View Paper: https://www.semanticscholar.org/paper/4decf9b11b26aeedf87ad0206f6d63a632e9002c

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In Immunology

1. Yong‐jun Liu
2. M. Gilliet
3. Shizuo Akira
4. Jacques Banchereau
5. R. Medzhitov
6. Rafi Ahmed
7. Bali Pulendran

Citations in the corpus

• Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus (2015, result): “Study by Hom et al. We analyzed data from a previous GWAS of SLE (Hom et al.4), which comprised 1,165 cases after our quality control analysis (Supplementary Note).”
• Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA–Peptide Complexes in Systemic Lupus Erythematosus (2011, background): “Y. Molad, J. Buyon, D. C. Anderson, S. B. Abramson, B. N. Cronstein, Intravascular neutrophil activation in systemic lupus erythematosus (SLE): Dissociation between increased expression of CD11b/CD18 and diminished expression of L-selectin on neutrophils from patients with active SLE.”
• Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations (2010, result): “Our method confirms prior results in the literature suggestive of disease effects mediated through expression (ORMDL3 for asthma risk [13], C8orf13 locus for lupus risk [20], SLC22A5 for Crohn’s disease [12,21]).”