Faculty Opinions recommendation of Multiplexed gene synthesis in emulsions for exploring protein functional landscapes.

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Unified rational protein engineering with sequence-based deep representation learning (2019, methodology): “Coupled with the continued proliferation of cheap DNA synthesis/assembly technologies 55 , and methods for digitized and multiplexed phenotyping, UniRep-guided protein design promises to accelerate the pace with which we can build biosensors 13 , protein 56 and DNA binders 57 and genome editing…”
Mega-scale experimental analysis of protein folding stability in biology and design (2023, background): “Advances in DNA synthesis 47,48 will also make it possible to expand cDNA display proteolysis beyond the largest domains studied here (72 amino acids).”