Rheological properties of peptide-based hydrogels for biomedical and other applications
By Congqi Yan, Darrin J. Pochan. Chemical Society Reviews, 2010
718 citations recorded by the source corpus.
Peptide-based hydrogels are an important class of biomaterials finding use in food industry and potential use in tissue engineering, drug delivery and microfluidics. A primary experimental method to explore the physical properties of these hydrogels is rheology. A fundamental understanding of peptide hydrogel mechanical properties and underlying molecular mechanisms is crucial for determining whether these biomaterials are potentially suitable for biotechnological uses. In this critical review, we cover the literature containing rheological characterization of the physical properties of peptide and polypeptide-based hydrogels including hydrogel bulk mechanical properties, gelation mechanisms, and the behavior of hydrogels during and after flow.
Subfields: Biomaterials, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/4dc9971f7646a488327d3936e36215ce2fde70f2
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In Biomaterials
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Citations in the corpus
- Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning (2018, background): “…formed from dilute polymer chains with given structure and properties, obtained either by intermolecular (polymer network) or by interfibrillar crosslinks (supramolecular fibrillary hydrogel network) (Tibbitt and Anseth, 2009; Li and Deming, 2010; Yan and Pochan, 2010; Worthington et al., 2015).”
- Low-Molecular-Weight Gels: The State of the Art (2017, positive): “Finally, the mechanical properties of the gels can be measured by techniques such as rheology.(52) A range of different measurements are possible and are able to inform on the gel networks.”