Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy.

By Hans Lassmann, Wolfgang Brück, C. Lucchinetti. Trends in Molecular Medicine, 2001

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Mechanisms Underlying Inflammation in Neurodegeneration (2010, neutral): “MS lesions are characterized by infiltration of lymphocytes and antibody-producing plasma cells into the perivascular region of the brain and spinal cord white matter, an increase in microglia and astrocytes, and demyelination (Lassmann et al., 2001).”
Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy (2008, background): “INTRODUCTION Multiple sclerosis (MS) is the most common demyelinating disease in young adults, and manifests itself in different ways (Lassmann et al., 2001).”
Experimental autoimmune encephalomyelitis repressed by microglial paralysis (2005, background): “Immunomodulatory compounds, including IFN-β, copolymer I and statins, can repress CNS autoimmune diseases including EA”
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. (2006, background): “The immunopathological classification of actively demyelinating focal plaques in acute and relapsing multiple sclerosis led to the definition of distinct pathological patterns in lesions [reviewed in Lassmann et al. (2001)].”