The miR-34 family in cancer and apoptosis

By H. Hermeking. Cell Death and Differentiation, 2010

1,263 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4d02ccfca4d15ad089fbd268d481e40d0d35a395

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. J. Campisi
2. P. Jat
3. R. Kumari
4. M. Collado
5. Manuel Serrano
6. H. Hermeking

In Molecular Biology

1. M. Demaria
2. J. Campisi
3. P. Jat
4. R. Kumari
5. Manuel Serrano
6. Masashi Narita
7. E. Hara
8. A. Alimonti

Citations in the corpus

• Cellular Senescence: Defining a Path Forward. (2019, positive): “However, the DDR also plays a major role in triggering OIS (Gorgoulis and Halazonetis, 2010; Gorgoulis et al., 2018; Halazonetis et al., 2008).”
• Mechanisms of Cellular Senescence: Cell Cycle Arrest and Senescence Associated Secretory Phenotype (2021, background): “…2018; Baker et al., 2019; Barnes et al., 2019). miR 124, miR-34a/b/c, and miR-29a/b/c are upregulated in response to p53 activation and facilitate cellular senescence by downregulating survival and cell proliferation factors (Hermeking, 2010; Boon et al., 2013; Hu et al., 2014; Xu S. et al., 2019).”
• miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions (2011, background): “Ectopic expression of miR‐34a and miR‐34b/c induces apoptosis, senescence, cell cycle arrest and inhibits migration and invasion.(2,3,11) Therefore, miR‐34a/b/c may be an important mediator of p53’s tumor-suppressive activities.”