Induction of pluripotent stem cells from fibroblast cultures

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How researchers see this paper

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Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition (2008, methodology): “We first infected mouse embryo fibroblasts (MEFs) with retroviruses harbouring the reprogramming factors Oct4, Sox2, c-MycT58, and Klf4 exactly as described [2,12].”
Alzheimer’s disease: experimental models and reality (2017, background): “The development of induced pluripotent stem cells (iPSCs) addresses this limitation [153].”
Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy (2011, methodology): “Retroviruses encoding Oct4 , Sox2 , Klf4 and c-Myc were individually packaged in PLAT-E cells using pMXs-based vectors (Addgene) and infections were carried out as previously describe”
Gene therapy clinical trials worldwide to 2012 – an update (2013, methodology): “that somatic cells can be reprogrammed to a state of pluripotency through the ectopic expression of as little as four transcription factors [75,76] has the potential to be a powerful tool for both gene and cellular therapies and to revolutionise”