Clinical significance of the bicuspid aortic valve

By C. Ward. Heart, 2000

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Bicuspid aortic valve is heritable. (2004, background): “Bicuspid aortic valve is frequently found underlying ortic stenosis; in pediatric patients 70% to 85% of stenotic ortic valves are bicuspid (4), and at least 50% of adults with ortic stenosis have BAV (5).”
Outcomes in adults with bicuspid aortic valves. (2008, background): “present and prior studies can be attributed to differences in the era that patients were examined, the population that was examined, the frequency of cardiac events associated with high mortality (aortic dissection and endocarditis), and advances in perioperative management.(1,2,4,5,23) The Olmsted ”
Bicuspid aortic valve disease. (2010, background): “Although adults with BAV often have ome degree of aortic regurgitation, the actual prevalence of ure aortic incompetence has varied, with some suggesting t is rare and others suggesting that it is common (3,71,72).”
Incidence of aortic complications in patients with bicuspid aortic valves. (2011, background): “Thus, it is estimated that BAV is responsible for more deaths than all other congenital heart defects combined.(13) Consequently, carriers live under the threat of sudden death.”