Metalloprotease-disintegrin (ADAM) genes are widely and differentially expressed in the adult CNS.

By I. Kärkkäinen, E. Rybnikova, M. Pelto-huikko, A. Huovila. 2000

137 citations recorded by the source corpus.

Subfields: Cell Biology, Immunology and Allergy, Molecular Biology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. P. Saftig

In Immunology and Allergy

1. S. Zhong
2. R. Khalil

In Molecular Biology

1. D. Edwards
2. S. Zhong
3. R. Khalil
4. P. Saftig
5. B. de Strooper

Citations in the corpus

• A Disintegrin and Metalloproteinase (ADAM) and ADAM with Thrombospondin Motifs (ADAMTS) Family in Vascular Biology and Disease (2019, background): “ADAM-12L can mediate cardiomyocyte hypertrophy by controlling the shedding of HBEGF [71, 72], and Notch signal pathway [73], and thereby regulates the disease progression [73, 74].”
• The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts. (2002, background): “Furthermore, it is well expressed in neurons throughout the CNS (34).”
• Metalloproteinases in biology and pathology of the nervous system (2001, background): “By contrast, in the case of ADAMs, over 17 family members are normally expressed in the adult CNS (REF. 9 ).”