d-Dimer for the Exclusion of Acute Venous Thrombosis and Pulmonary Embolism

By P. Stein, R. Hull, K. Patel, Ronald E. Olson, W. Ghali, R. Brant, Rita K. Biel, V. Bharadia, N. Kalra. Annals of Internal Medicine, 2004

831 citations recorded by the source corpus.

Subfields: Hematology, Internal Medicine, Neurology

View Paper: https://www.semanticscholar.org/paper/4c0f7cba103f9f3b30828872b9c88931d296ed12

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Hematology

S. Konstantinides

In Internal Medicine

Citations in the corpus

D-dimer antigen: current concepts and future prospects. (2009, methodology): “In a large meta-analysis, Stein et al demonstrated that a negative D-dimer test by the rapid ELISA method is as diagnostically useful as a negative computerized tomography (CT) or a negative compression ultrasonography study (CUS) in excluding PE and DVT respectively.(45) However, recent surveys ind”
[2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism]. (2014, positive): “A number of D-dimer assays are available.(110,111) The quantitative enzyme-linked immunosorbent assay (ELISA) or ELISA-derived assays have a diagnostic sensitivity of 95% or better and can therefore be used to exclude PE in patients with either a low or a moderate pre-test probability.”
Guidelines on the Diagnosis and Management of Acute Pulmonary Embolism (2008, background): “Quantitative latex-derived assays and a whole-blood agglutination assay have lower sensitivity, in the range of 85–90%, and are often referred to as moderately sensitive assays.(75,76) The most extensively studied to date in outcome studies are the Tinaquant and the SimpliRED assays, which yield a 3”
ESC Guidelines on the diagnosis and management of acute pulmonary embolism (2014, background): “A number of D-dimer assays are available.(110,111) The quantitative enzyme-linked immunosorbent assay (ELISA) or ELISA-derived assays have a diagnostic sensitivity of 95% or better and can therefore be used to exclude PE in patients with either a low or a moderate pre-test probability.”