Prevention of Preeclampsia and Intrauterine Growth Restriction With Aspirin Started in Early Pregnancy: A Meta-Analysis

By E. Bujold, S. Roberge, Y. Lacasse, M. Bureau, F. Audibert, S. Marcoux, J. Forest, Y. Giguère. Obstetrics and Gynecology, 2010

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The hypertensive disorders of pregnancy: ISSHP classification, diagnosis & management recommendations for international practice. (2018, background): “43 setting of low calcium intake) are recommended for the prevention of preeclampsia(62-64).”
The 2021 International Society for the Study of Hypertension in Pregnancy classification, diagnosis & management recommendations for international practice. (2021, background): “Women who book late for antenatal care may still benefit from aspirin started after 16 weeks, although the reduction in pre-eclampsia has been estimated to be non-significant [109].”
ESH / ESC Guidelines for the management of arterial hypertension (2013, background): “09) compared with control.(505) Faced with these discrepant data, only prudent advice can be offered: women at high risk of pre-eclampsia (from hypertension in a previous preg-”
The role of aspirin dose on the prevention of preeclampsia and fetal growth restriction: systematic review and meta‐analysis (2017, positive): “Therefore, these authors performed a systematic review and meta-analyses of randomized controlled trials and evaluated the dose-response effect of aspirin on the prevention of PE and FGR. PE was defined as systolic blood pressure Z140mm Hg or diastolic blood pressure Z90mm Hg occurring after 20 week”