Impact of mutational testing on the diagnosis and management of patients with cytologically indeterminate thyroid nodules: a prospective analysis of 1056 FNA samples.

By Y. Nikiforov, N. Ohori, S. Hodak, S. Carty, S. Lebeau, R. Ferris, L. Yip, R. Seethala, M. Tublin, M. Stang and 4 more. Journal of Clinical Endocrinology and Metabolism, 2011

703 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/2d89e6c762250e517286c1ae5ad0e4cf900d2ebb

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology, Diabetes and Metabolism

Y. Nikiforov

In Molecular Biology

Citations in the corpus

Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer (2015, background): “[B5] ARE THERE MOLECULAR SIGNATURES THAT COMPLEMENT FNA AND IMPROVE THE DIAGNOSTIC UTILITY OF FNA IN CHILDREN? Studies in adults have shown that molecular testing aids in the management of thyroid nodules with indeterminate cytopathology (125-130).”
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer (2009, positive): “In indeterminate cytology thyroid nodules, the sensitivity of the sevengene mutational panel testing is variable, with reports ranging from 44% to 100% (162,165,167).”
Integrated Genomic Characterization of Papillary Thyroid Carcinoma (2014, background): “Molecular testing of mutation hotspots, rearrangements, and gene expression using fine-needle aspiration specimens has become an effective diagnostic tool to more precisely select patients for thyroid surgery (Alexander et al., 2012; Nikiforov et al., 2011), thereby reducing the number of thyroidect”