COVID-19: Epidemiology, Evolution, and Cross-Disciplinary Perspectives
By Jiumeng Sun, Wanting He, Lifang Wang, A. Lai, X. Ji, Xiaofeng Zhai, Gairu Li, Marc A. Suchard, Jin Tian, Jiyong Zhou and 2 more. Trends in Molecular Medicine, 2020
600 citations recorded by the source corpus.
The recent outbreak of COVID-19 in Wuhan turned into a public health emergency of international concern. With no antiviral drugs nor vaccines, and the presence of carriers without obvious symptoms, traditional public health intervention measures are significantly less effective. Here, we report the epidemiological and virological characteristics of the COVID-19 outbreak. Originated in bats, 2019-nCoV/ severe acute respiratory syndrome coronavirus (SARS-CoV)-2 likely experienced adaptive evolution in intermediate hosts before transfer to humans at a concentrated source of transmission. Similarities of receptor sequence binding to 2019-nCoV between humans and animals suggest a low species barrier for transmission of the virus to farm animals. We propose, based on the One Health model, that veterinarians and animal specialists should be involved in a cross-disciplinary collaboration in the fight against this epidemic.
Subfields: Infectious Diseases, Modeling and Simulation
View Paper: https://www.semanticscholar.org/paper/4b54450b558b84a717664eb6eef0ce5f7b3c7182
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Citations in the corpus
- Using X-ray images and deep learning for automated detection of coronavirus disease (2020, background): “…would, therefore, to have originated from an animal (zoonosis) but the origin has not been confirmed (Boopathi et al., 2020; CNHC, 2020; El Zowalaty & J € arhult, 2020; Kandel et al., 2020; Manoj et al., 2020; Pant et al., 2020; Roosa et al., 2020; Sun et al., 2020; Wilder-Smith et al., 2020).”
- Laboratory diagnosis of emerging human coronavirus infections – the state of the art (2020, background): “An interesting question is the susceptibility of farm animals and pets, and their role in the epidemiologic cycle as their angiotensin-converting enzyme 2 (ACE2) receptor shares similarity with human ACE2 [14].”