The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling

By O. Nicole, F. Docagne, C. Ali, I. Margaill, Peter Carmeliet, E. Mackenzie, D. Vivien, A. Buisson. Nature Medicine, 2001

737 citations recorded by the source corpus.

Subfields: Cancer Research, Epidemiology, Hematology

View Paper: https://www.semanticscholar.org/paper/4b08e771da9b90a5290b58e3689c21601508f1ed

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Citations in the corpus

• LRP: a multifunctional scavenger and signaling receptor. (2001, background): “tPA has also been reported to potentiate NMDA receptor–mediated neurotoxicity via cleavage of the NR1 subunit of the NMDA receptor, leading to increased activity of the NMDA receptor (44).”