Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees.

By S. Wakitani, K. Imoto, Tetsuya Yamamoto, M. Saito, N. Murata, M. Yoneda. Osteoarthritis and Cartilage, 2002

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Same or Not the Same? Comparison of Adipose Tissue-Derived Versus Bone Marrow-Derived Mesenchymal Stem and Stromal Cells (2012, neutral): “tested the role of autologous BM-MSCs in the repair of large articular cartilage defects in the osteoarthritic knees of patients (n = 24) who underwent high tibial osteotomy [187].”
Challenges in tissue engineering (2006, background): “…2002), maxillary sinus augmentation (Rodriguez et al. 2003), metacarpophalangeal joints (Honkanen et al. 2003), osteoarthritic knee cartilage (Wakitani et al. 2002), osteochondritis dissecans (Ochi et al. 2002; Peterson et al. 2003), myocardial infarction (Wollert et al. 2004), vascular…”
Mesenchymal Stem Cells for Regenerative Medicine (2019, background): “Despite clinical trials being conducted, there are no commercially available products for MSC-based cartilage reconstruction [82,83].”
Articular cartilage defects: study of 25,124 knee arthroscopies. (2007, methodology): “Although many new techniques have been introduced [2–8] the treatment of traumatic and non-traumatic cartilage lesions remains a controversial challenge.”