Prepregnancy BMI and the risk of gestational diabetes: a systematic review of the literature with meta‐analysis
By M. Torloni, A P Betrbn, B. Horta, M. Nakamura, Á. N. Atallah, A F Moron, O. Valente. Obesity Reviews, 2009
740 citations recorded by the source corpus.
The objective of this study is to assess and quantify the risk for gestational diabetes mellitus (GDM) according to prepregnancy maternal body mass index (BMI). The design is a systematic review of observational studies published in the last 30 years. Four electronic databases were searched for publications (1977–2007). BMI was elected as the only measure of obesity, and all diagnostic criteria for GDM were accepted. Studies with selective screening for GDM were excluded. There were no language restrictions. The methodological quality of primary studies was assessed. Some 1745 citations were screened, and 70 studies (two unpublished) involving 671 945 women were included (59 cohorts and 11 case–controls). Most studies were of high or medium quality. Compared with women with a normal BMI, the unadjusted pooled odds ratio (OR) of an underweight woman developing GDM was 0.75 (95% confidence interval [CI] 0.69 to 0.82). The OR for overweight, moderately obese and morbidly obese women were 1.97 (95% CI 1.77 to 2.19), 3.01 (95% CI 2.34 to 3.87) and 5.55 (95% CI 4.27 to 7.21) respectively. For every 1 kg m−2 increase in BMI, the prevalence of GDM increased by 0.92% (95% CI 0.73 to 1.10). The risk of GDM is positively associated with prepregnancy BMI. This information is important when counselling women planning a pregnancy.
Subfields: Obstetrics and Gynecology, Surgery
View Paper: https://www.semanticscholar.org/paper/4aaea4d7cf9fa2b31aa9d62694d3b70ff9c01ada
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Obstetrics and Gynecology
Citations in the corpus
- Risks associated with obesity in pregnancy, for the mother and baby: a systematic review of reviews (2015, neutral): “Negative health outcomes of obesity in pregnant women Gestational diabetes mellitus The association between maternal obesity and gestational diabetes mellitus (GDM) was reported in two reviews (27,35) published in 2007 and 2009, involving both lowand high-income countries (Table 1).”
- Pre-Pregnancy Body Mass Index in Relation to Infant Birth Weight and Offspring Overweight/Obesity: A Systematic Review and Meta-Analysis (2013, background): “Prepregnancy overweight/obesity is a risk factor for diabetes mellitus (DM), hypertension, and preeclampsia in pregnancy [8–10].”