IgG4 production is confined to human IL-10-producing regulatory B cells that suppress antigen-specific immune responses.

By Willem van de Veen, B. Stanić, Görkem Yaman, M. Wawrzyniak, S. Söllner, Deniz Akdis, B. Rückert, Cezmi Akdis, M. Akdiş. Journal of Allergy and Clinical Immunology, 2013

620 citations recorded by the source corpus.

Subfields: Immunology, Immunology and Allergy

View Paper: https://www.semanticscholar.org/paper/4a4c512fccc09a90fb90eb0c0b4c500f6723efcb

How researchers see this paper

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In Immunology

1. E. Rosser
2. Cezmi Akdis
3. C. Mauri

Citations in the corpus

• Regulatory B cells: origin, phenotype, and function. (2015, background): “Despite considerable effort, no study that has performed gene arrays on Breg cells in both mice (Shen et al., 2014) and humans (van de Veen et al., 2013) has conclusively identified a lineage-specific marker equivalent to Foxp3.”
• Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: Receptors, functions, and roles in diseases. (2016, background): “IL-2 is essential for the development of Treg cells, and IL-2Ra is a marker for the flow cytometric identification of Treg and regulatory B (Breg) cells in resting conditions.(71,72) IL-2 is a regulator of ILCs and acts as a B-cell growth factor, stimulates antibody synthesis, and promotes prolifera”