α10: A determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells

By A. Elgoyhen, D. Vetter, E. Katz, C. Rothlin, S. Heinemann, J. Boulter. Proceedings of the National Academy of Sciences of the United States of America, 2001

706 citations recorded by the source corpus.

Subfields: Microbiology, Molecular Biology, Sensory Systems

View Paper: https://www.semanticscholar.org/paper/49f8a08754de65b03f36620c44605ff840109baa

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Cecilia Gotti
2. Sonia Bertrand
3. F. Clementi
4. Daniel Bertrand
5. Jean-Louis Reymond

Citations in the corpus

• A Novel Human Nicotinic Receptor Subunit, α10, That Confers Functionality to the α9-Subunit (2002, background): “In a very recent publication, Elgoyhen et al. (2001) have reported the cloning and characterization of the rat 10-subunit.”
• Neuronal nicotinic receptors: from structure to pathology. (2004, background): “The a10 subunit is similar to the a9 subunit by amino acid sequence (Elgoyhen et al., 2001; Sgard et al., 2002), but oocyte injections of the mRNA encoding the a10 subunit alone or in combination with mRNA encoding for the a2–a6 subunits or b2–b4 subunits give no detectable currents.”
• Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system--too little activation is bad, too much is even worse. (2007, background): “in cochlear hair cells, and this action is therefore highly unlikely to be responsible for therapeutic effects of memantine on symptoms in AD (Elgoyhen et al., 2001; Katz et al., 2004).”