HIF-1alpha expression regulates the bactericidal capacity of phagocytes.

By C. Peyssonnaux, V. Datta, T. Cramer, A. Doedens, E. Theodorakis, R. Gallo, Nancy Hurtado-Ziola, V. Nizet, Richard J. Johnson. Journal of Clinical Investigation, 2005

748 citations recorded by the source corpus.

Subfields: Biotechnology, Cancer Research, Neurology

View Paper: https://www.semanticscholar.org/paper/49f157e4cdad519b6d871df6b3d076b4cdb201fc

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. V. Nizet
2. A. Chawla
3. A. Palazón
4. Richard J. Johnson
5. Ananda W. Goldrath
6. G. Semenza

In Neurology

1. A. Chawla
2. P. Murray

Citations in the corpus

• Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation. (2006, background): “Pharmacological inhibition of glycolysis or genetic deletion of HIF-1α in myeloid cells greatly reduces cellular ATP content and has the functional consequence of diminishing their antimicrobial activity (Cramer et al., 2003;Peyssonnaux et al., 2005).”
• HIF Transcription Factors, Inflammation, and Immunity (2014, background): “In these studies HIF-1a was correlated with iNOS expression, driving NO and TNF-a production; these in turn have an important role in regulating the antimicrobial action of myeloid cells (Peyssonnaux et al., 2005).”