Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition.

357 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Studying multisite binary and ternary protein interactions by global analysis of isothermal titration calorimetry data in SEDPHAT: Application to adaptor protein complexes in cell signaling (2007, methodology): “This software is a widely used platform for the global analysis of analytical ultracentrifugation and dynamic light scattering data, as well as general binding isotherms for a variety of biophysical techniques (Vistica al.”
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase (2011, methodology): “and equilibrium data were analysed using the program SEDPHA”
Protein aggregation: pathways, induction factors and analysis. (2009, methodology): “where the data analysis is based on the continuous sedimentation coefficient distribution method.(138,150) The programs allow fast and rigorously data analysis by fitting the SV data using the Lamm’s equation(151) and thus enable to detect, quantify and characterize small amounts of protein aggregat”