OrthoVenn: a web server for genome wide comparison and annotation of orthologous clusters across multiple species
By Yi Wang, Devin Coleman-Derr, Guoping Chen, Yong Qiang Gu. Nucleic Acids Res., 2015
458 citations recorded by the source corpus.
Genome wide analysis of orthologous clusters is an important component of comparative genomics studies. Identifying the overlap among orthologous clusters can enable us to elucidate the function and evolution of proteins across multiple species. Here, we report a web platform named OrthoVenn that is useful for genome wide comparisons and visualization of orthologous clusters. OrthoVenn provides coverage of vertebrates, metazoa, protists, fungi, plants and bacteria for the comparison of orthologous clusters and also supports uploading of customized protein sequences from user-defined species. An interactive Venn diagram, summary counts, and functional summaries of the disjunction and intersection of clusters shared between species are displayed as part of the OrthoVenn result. OrthoVenn also includes in-depth views of the clusters using various sequence analysis tools. Furthermore, OrthoVenn identifies orthologous clusters of single copy genes and allows for a customized search of clusters of specific genes through key words or BLAST. OrthoVenn is an efficient and user-friendly web server freely accessible at http://probes.pw.usda.gov/OrthoVenn or http://aegilops.wheat.ucdavis.edu/OrthoVenn.
Subfields: Genetics, Molecular Biology, Plant Science
View Paper: https://www.semanticscholar.org/paper/4941e29186ebfac8f706eeb98488c45fea86fb28
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Citations in the corpus
- OrthoVenn2: a web server for whole-genome comparison and annotation of orthologous clusters across multiple species (2019, methodology): “We downloaded protein sequence from the Ensembl database (release January 2019) and incorporated them into OrthoVenn2 following our previous pipeline (25).”