Lateral flow (immuno)assay: its strengths, weaknesses, opportunities and threats. A literature survey
By Geertruida A. Posthuma-Trumpie, J. Korf, A. Amerongen. Analytical and Bioanalytical Chemistry, 2009
1,442 citations recorded by the source corpus.
Lateral flow (immuno)assays are currently used for qualitative, semiquantitative and to some extent quantitative monitoring in resource-poor or non-laboratory environments. Applications include tests on pathogens, drugs, hormones and metabolites in biomedical, phytosanitary, veterinary, feed/food and environmental settings. We describe principles of current formats, applications, limitations and perspectives for quantitative monitoring. We illustrate the potentials and limitations of analysis with lateral flow (immuno)assays using a literature survey and a SWOT analysis (acronym for “strengths, weaknesses, opportunities, threats”). Articles referred to in this survey were searched for on MEDLINE, Scopus and in references of reviewed papers. Search terms included “immunochromatography”, “sol particle immunoassay”, “lateral flow immunoassay” and “dipstick assay”.
Subfields: Biomedical Engineering, Infectious Diseases, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/492631376d3934836a83b5990933092e99657427
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Citations in the corpus
- Smartphone based bacterial detection using biofunctionalized fluorescent nanoparticles (2014, background): “Simple immunoassay protocols have become increasingly common at resource – limited sites, particularly in the form of lateral flow immunoassay (LFIA) for testing pregnancy, drug of abuse, diagnosis of various diseases and environmental monitoring [2].”
- A simple and compact smartphone accessory for quantitative chemiluminescence-based lateral flow immunoassay for salivary cortisol detection. (2015, background): “This is because they are low cost and easy to handle, thanks to the use of capillary force for fluid transport and delivery without external power (Ballerini et al., 2012; Li et al., 2011; Martinez et al., 2008; Martinez et al., 2010; Posthuma-Trumpie et al., 2009; Zhao and Van der Berg, 2008).”
- Towards the Optimization of eDNA/eRNA Sampling Technologies for Marine Biosecurity Surveillance (2021, methodology): “These approaches do not require thermal cycling and operate at much lower temperatures, with the end-point analysis of amplified products in the field possible using lateral flow (LF) strips, similar to those used in pregnancy test kits [190].”
- Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications. (2010, methodology): “The fact that 6 billion glucose test strips were sold in 2007 [88] already indicates that the LAT may be seen as a gold-standard microfluidic platform in terms of cost, handling simplicity, robustness, market presence and the number of implemented lab-on-a-chip applications [69].”