Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

By K. Coppieters, F. Dotta, N. Amirian, Peter D. Campbell, T. Kay, Mark Atkinson, B. Roep, M. V. von Herrath. Journal of Experimental Medicine, 2012

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In situ tetramer staining reveals the presence of islet antigen-reactive CD8+ T cells in pancreatic islets from deceased type 1 diabetes patients.

Subfields: Endocrinology, Diabetes and Metabolism, Genetics, Surgery

View Paper: https://www.semanticscholar.org/paper/479d28b7cd35c2af78f3a9c586547cd8c284080c