Collagen-Based Biomaterials for Wound Healing
By Sayani Chattopadhyay, Ronald T. Raines. Biopolymers, 2014
899 citations recorded by the source corpus.
With its wide distribution in soft and hard connective tissues, collagen is the most abundant of animal proteins. In vitro, natural collagen can be formed into highly organized, three‐dimensional scaffolds that are intrinsically biocompatible, biodegradable, nontoxic upon exogenous application, and endowed with high tensile strength. These attributes make collagen the material of choice for wound healing and tissue engineering applications. In this article, we review the structure and molecular interactions of collagen in vivo; the recent use of natural collagen in sponges, injectables, films and membranes, dressings, and skin grafts; and the on‐going development of synthetic collagen mimetic peptides as pylons to anchor cytoactive agents in wound beds. © 2014 Wiley Periodicals, Inc. Biopolymers 101: 821–833, 2014.
Subfields: Biomaterials, Biomedical Engineering
View Paper: https://www.semanticscholar.org/paper/474ab4db64947753c1b48c4109daaf5a5d245df3
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Citations in the corpus
- Treatment Strategies for Infected Wounds (2018, background): “Collagens (A): They are in the form of pads, gels or particles and encourage the formation and setting of new- formed collagen in wounds, they absorb exudates, offer a humid environment to wounds; They are easy to apply, non-immunogenic, non-pyrogenic, (D): Not recommended to application to wounds w”
- Current development of biodegradable polymeric materials for biomedical applications (2018, background): “and physicochemical properties; nontoxicity; and high tensile strength, collagen has been widely studied for biomedical applications.(16,17) Collagen plays a critical role in preserving the biological and structural integrity of the ECM and is highly dynamic, undergoing continuous remodeling for pro”