Immunotoxin and Taxol synergy results from a decrease in shed mesothelin levels in the extracellular space of tumors

By Yujian Zhang, Laiman Xiang, R. Hassan, I. Pastan. 2007

87 citations recorded by the source corpus.

Subfields: Biotechnology, Immunology, Radiology, Nuclear Medicine and Imaging

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1. Vincent Zangiacomi
2. K. Asgarov
3. H. de Haard
4. Charline Tirole
5. M. González-Pajuelo
6. J. Wijdenes
7. Diana Ramos
8. António Barroso

Citations in the corpus

• A new anti-mesothelin antibody targets selectively the membrane-associated form (2017, methodology): “One possible explanation for the lack of efficacy might be the presence of soluble mesothelin in the blood as well as in the extracellular space of tumors, which could reduce the efficacy of the therapeutic mAb by competition.(22) A recent study demonstrated that reduced shedding of surface mesothel”