MAOA, maltreatment, and gene–environment interaction predicting children's mental health: new evidence and a meta-analysis

By Julia Kim-Cohen, Avshalom Caspi, Alan H. Taylor, B. Williams, R. Newcombe, I. Craig, Terrie E. Moffitt. Molecular Psychiatry, 2006

1,142 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Clinical Psychology, Safety Research

View Paper: https://www.semanticscholar.org/paper/46f18c81cd7cb49dca83f502f0b4089e801e9166

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Citations in the corpus

Two Genes Predict Voter Turnout (2008, positive): “Rhesus macaque monkeys with impaired serotonin metabo-lisms are impulsive and aggressive in response to social stressors (Kraemer et al. 1989) and studies of rodents show that acute emotional stress affects the way MAOA breaks down serotonin in several areas of the brain (Popova, Voitenko, and Maslo”
Beyond diathesis stress: differential susceptibility to environmental influences. (2009, background): “For example, Kim-Cohen et al. (2006) found that at age 7 years boys with the low-MAOAactivity variant were rated by mothers and teachers as having more mental health problems—and specifically symptoms of attentiondeficit/hyperactivity disorder (ADHD)—if they had been victims of abuse, but fewer…”
Genetics of the Human Personality (2010, background): “In a meta-analysis of five independent studies on MAOA, maltreatment, and gene-environment interaction predicting children ́s mental health, Kim-Cohen et al. (2006) demonstrated that the association between maltreatment and mental health problems is significantly stronger in the group of males.”
Systematic reviews of explanatory risk factors for violence, offending, and delinquency (2017, background): “Kim-Cohen et al. (2006) Review of the interaction between the MAOA gene and child maltreatment, and resulting outcomes, such as child mental health difficulties and antisocial behavior.”
From Genes to Brain to Antisocial Behavior (2008, background): “One meta-analysis shows replicability of this interaction effect (Kim-Cohen et al., 2006), although inevitably there are environmental complexities that require further clarification.”
Measured Gene–Environment Interactions and Mechanisms Promoting Resilient Development (2009, result): “…before these G E hypotheses can be definitively confirmed, both findings have been replicated in several independent studies and a meta-analysis (Kim-Cohen et al., 2006; Taylor & Kim-Cohen, 2007; Uher & McGuffin, 2007), indicating that, rather than having a direct and linear association to…”
“The Biological Effects of Childhood Trauma” (2014, positive): “Meta-analyses revealed that the association between early family adversity (particularly between neglect or physical abuse) and the short version of the MAOA gene was significantly associated with a general index of mental health problems, antisocial behavior, attentional problems, and hyperactivity”