A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

By R. Hung, J. Mckay, V. Gaborieau, P. Boffetta, M. Hashibe, D. Zaridze, A. Mukeria, N. szeszenia-Dabrowska, J. Lissowska, P. Rudnai and 55 more. Nature, 2008

1,289 citations recorded by the source corpus.

Subfields: Epidemiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/460ca023bb028d3a61995db1f5c68230e65c8f62

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Citations in the corpus

p53 polymorphisms: cancer implications (2009, neutral): “i1 i2 i3 i4 i5 i6 i7 i8 i9 i10 (41, 10,739) (1, 115) (2, 92) (5, 775) (2, 81) (4, 567) (7, 342) (1, 92) (13, 2,817) (5, 919) Transactivation domains Prolinerich domain DNA-binding domain Tetramerization domain”
iArc monogrAphs on the evAluAtion oF cArcinogenic risks to humAns (2012, result): “Although subject to some uncertainty, these results suggest that about 8–15% of the lung cancer deaths in Europe and North America may be attributed to residential radon exposure, making radon the second leading cause of lung cancer death after tobacco smoking in those regions.”
Genotype Imputation (2009, background): “Hung (41) Nature 2008/04 MACH A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25”
Systems medicine: the future of medical genomics and healthcare (2009, background): “significant problems with signal-to-noise ratios that still severely limit the conclusions that can be drawn from such studies, progress has been made in identifying susceptibility loci involved in, for example, diabetes [161-163], obesity [164], and breast or lung cancer [165-167].”
Sequence variants at the TERT- CLPTM1L locus associate with many cancer types (2009, neutral): “…the dataset on colorectal cancer from the U.K. Institute of Cancer Research (ICR) 27 , the dataset on lung cancer from the International Agency for Research on Cancer (IARC) 11 and the datasets on prostate and breast cancer from the Cancer Genetics Markers of Susceptibility (CGEMS) study group 4 .”
Non-small cell lung cancer: current treatment and future advances. (2016, background): “There are also reports of a marker on chromosome 15 associated with lung cancer, which was explored in three independent genetic studies (28-30).”
A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci (2009, background): “The association of smoking dependence was explored in the lung cancer report by Hung and colleagues [13] who did not detect any association with individual Fagerstrom indices of nicotine addiction or when comparing controls with a heaviness of smoking index (HSI).”