Juicebox.js Provides a Cloud-Based Visualization System for Hi-C Data

By James T. Robinson, Douglass Turner, Neva C. Durand, Helga Thorvaldsdóttir, Jill P. Mesirov, Erez Lieberman Aiden. bioRxiv, 2017

480 citations recorded by the source corpus.

Contact mapping experiments such as Hi-C explore how genomes fold in 3D. Here, we introduce Juicebox.js, a cloud-based web application for exploring the resulting datasets. Like the original Juicebox application, Juicebox.js allows users to zoom in and out of such datasets using an interface similar to Google Earth. Furthermore, Juicebox.js encodes the exact state of the browser in a shareable URL. Creating a public browser for a new Hi-C dataset does not require coding and can be accomplished in under a minute.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/457d7ccecbe2d001e9a983cb5ef593f1f9d85c51

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Citations in the corpus

• New developments on the Encyclopedia of DNA Elements (ENCODE) data portal (2019, methodology): “…of Hi-C re-sults, portal pages for these experiments were modified to include links, which can be found on the ‘File details’ tab, redirecting to the Juicebox visualization software web page (https://aidenlab.org/juicebox/) and to allow selection of the relevant files for visualization (30,31).”