Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry.

By D. Bandura, V. Baranov, O. Ornatsky, A. Antonov, R. Kinach, X. Lou, S. Pavlov, S. Vorobiev, J. Dick, S. Tanner. Analytical Chemistry, 2009

1,191 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Molecular Biology, Spectroscopy

View Paper: https://www.semanticscholar.org/paper/451bfb7906f7b02fd2104ce143f95bb83be6aa4e

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In Biomedical Engineering

1. Holden T. Maecker

In Molecular Biology

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Citations in the corpus

• SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation (2017, methodology): “Multiple antibody-based methods for quantifying proteins in single cells have been recently developed, including CyTOF [7, 8], single-cell Western blots [9], and Proseek Multiplex, an immunoassay readout by PCR [10].”
• Standardizing immunophenotyping for the Human Immunology Project (2012, background): “Another new technology, mass cytometry (CyTOF, DVS Sciences), is poised to revolutionize flow cytometry by allowing many more antibody probes to be combined in a single assay, while simultaneously eliminating the issue of optical spillover”
• Single-Cell and Single-Molecule Analysis of Gene Expression Regulation (2016, background): “FACS is useful to catalog cell types based on the combination of protein markers (5).”
• Categorical Analysis of Human T Cell Heterogeneity with One-Dimensional Soli-Expression by Nonlinear Stochastic Embedding (2016, background): “More recently, high-dimensional polychromatic flow cytometry (2), mass cyto-metry (3), and high-throughput single-cell transcriptomics (4–6) approaches allow for identification of multiple subpopulations of cells and the ability to probe relationships between expression levels of large numbers of…”
• Cytofkit: A Bioconductor Package for an Integrated Mass Cytometry Data Analysis Pipeline (2016, background): “Mass cytometry, or cytometry by time-of-flight (CyTOF), uniquely combines metal-labeling of antibodies with mass spectrometry to enable high-dimensional measurement of the characteristics of individual cells [1,2].”