β‐1,6‐Glucan synthesis in Saccharomyces cerevisiae

By S. Shahinian, H. Bussey. 2000

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Cell Wall Integrity Signaling in Saccharomyces cerevisiae (2005, background): “Genetic analyses revealed 1,6-glucan synthesis mutations in genes that function throughout the secretory pathway (249, 301), suggesting that biosynthesis of this polymer begins in the endoplasmic reticulum, progresses in the Golgi, and is completed at the cell surface.”
Cell Wall Assembly in Saccharomyces cerevisiae (2006, methodology): “glucan have been reviewed (210, 256), and earlier work will”
Regulation of Cell Wall Biogenesis in Saccharomyces cerevisiae: The Cell Wall Integrity Signaling Pathway (2011, background): “…been controversial for many years. b-1,6-glucan synthesis defects are caused by mutations in genes that function throughout the secretory pathway (Shahinian and Bussey 2000; Page et al. 2003), suggesting that biosynthesis of this polymer begins in the endoplasmic reticulum (ER), progresses in…”
In situ localization of β‐glucans in the cell wall of Schizosaccharomyces pombe (2001, background): “This location is in agreement with the hypothesis that b-1,6-glucan connects the proteins in the mannoprotein layer to the cell wall (de Nobel and Lipke, 1994; Osumi, 1998; Shahinian and Bussey, 2000).”
The Fungal Cell Wall: Structure, Biosynthesis, and Function (2017, background): “Many of these KRE genes such as KRE2 , KRE5 , KRE6 , and KRE9 impact glucan synthesis without being directly associated with an enzymatic activity (9, 62).”